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Encapsulation of Fluoroquinolones in 1-Palmitoyl-2-Myristoyl- Phosphatidylcholine: Cholesterol Liposomes

Sousa Isabel and Gameiro Paula

Encapsulation of Fluoroquinolones in 1-Palmitoyl-2-Myristoyl- Phosphatidylcholine: Cholesterol Liposomes

CQuinolones are a very well known class of antibacterial agents and, currently, one of the most prescribed drugs in medicine, therefore having a wide use in the treatment of several bacterial infections which seems to be the main cause for their bacterial resistance. With increasing menace of bacterial resistance, the development of new strategies to increase its efficacy is of great importance. Liposomes have been under study as drug delivery systems for the past years mainly due to their high biocompatibility in terms of composition, size and physicochemical properties.