மருந்து அறிவியல் மற்றும் வளர்ந்து வரும் மருந்துகளின் இதழ்

First Dose Combination Studies of Anti-Tuberculosis Drugs With Piperic Acid

Gabriel Oliveira de Resende, Bruno Almeida Cotrim,Emerson Teixeira da Silva, Maria Cristina Silva Louren'o, Bruna Vitor de Almeida Rito, and Marcus Vin?cius Nora de Souza

First Dose Combination Studies of Anti-Tuberculosis Drugs With Piperic Acid

The combinatorial effect of piperic acid with various anti-tuberculosis (anti-TB) drugs was evaluated in vitro against Mycobacterium tuberculosis. The present study has demonstrated for the first time that a combination of piperic acid with rifampicin imparts a synergic effect against M. tuberculosis.