உயிர் பொருட்கள் மற்றும் மருத்துவ பயன்பாடுகள்

Zinc-doped Calcium Phosphate Coating on Titanium Surface Using Ostrich Eggshell as a Ca2+ Ions Source

Ferreira JRM, Louro LHL, Costa AM, Marçal RLSB, Navarro da Rocha D, Barbosa RM, Campos JB and Prado da Silva MH

Natural calcium source materials can be thermochemically processed and directly transformed into hydroxyapatite. In this work, ostrich eggshell was used as Ca2+ ions source in the preparation of zinc-calcium phosphate coatings on Ti substrates promoted by a two-step deposition method. The obtained coatings were characterized by X-ray diffraction (XRD) analysis, scanning electron microscopy with field emission gun (FEG-SEM), bioactivity using McCoy medium and toxicity with chicken embryo chorioallantoic membrane (CAM). The results showed the presence of Znbrushite and Zn-hydroxyapatite as coating phases. Bioactivity was observed in all samples showing bone-like apatite on their surface. The toxicity test showed inflammatory response between mild to moderate confirming the material’s biocompatibility. The use of ostrich eggshells was shown to be effective as a Ca2+ ions source to obtain zinc-containing hydroxyapatite coatings on Ti substrates.