Maria Francesca Zenobii, Stefano Ballestri, Amedeo Lonardo, Silvia Ognibene, Enrica Baldelli, Dante Romagnoli and Paola Loria
“To Treat or Not to Treat?”: A Case of Severe Acute Hepatitis-B Treated with Entecavir Compared to a Case of Milder, Untreated Disease
Purpose: Acute hepatitis B, usually a benign disease in the immunocompetent adult, may be fatal in a minority of cases. The oral deoxyguanosine nucleoside analogue entecavir has gained a definite role in treating chronic hepatitis B virus infection. However, the indications and the specific timing for antiviral treatment in severe AHB remains to be established. We aimed at gaining insight into such indication based on clinical observation of two cases.
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