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Ultraviolet-A Light Induces Micronucleated Erythrocytes in Newborn Rats

Guillermo M Zuniga-Gonzalez, Belinda C Gomez-Meda, Ana L Zamora-Perez, Maria A Martínez-Gonzalez, Juan Armendáriz- Borunda, Blanca P Lazalde-Ramos, Yveth M Ortiz-García and Martha P Gallegos-Arreola

Ultraviolet-A Light Induces Micronucleated Erythrocytes in Newborn Rats

Ultraviolet-A (UV-A) light induce DNA damage by creating pyrimidine dimers, or indirectly affects DNA by the formation of reactive oxygen species. The objective was to determine DNA damage by micronucleus test in neonatal rats exposed to UV-A light. Rat neonates were exposed to light from a LED lamp (control group), to UV-C light 254 nm (control group to desquamation skin) or UV-A light 365 nm and in one group the dams were supplemented with folic acid (FA), to determine micronucleated erythrocytes (MNE) and micronucleated polychromatic erythrocytes (MNPCE) in peripheral blood of offspring.